It is common for a teleserye to encounter changes either before or during its production. Some changes are caused by schedules, location changes, etc.
Sometimes, the artists included in teleseryes can cause changes in the production, as some get pregnant, experience personal problems, or worse, encounter death.
The last teleserye to encounter this change was the afternoon teleserye All of Me, wherein its lead star JM de Guzman encountered a personal problem that triggered production to pull him out of the show.
Here are some stars who had to leave a teleserye due to unforeseen circumstances:
PEP Live